Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599216 | 0.86 | TSHR (0.45) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL28657384 | 0.85 | TSHR (0.44) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL1613917 | 0.82 | TSHR (0.48) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL7936478 | 0.81 | AGTR2 (0.45) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL5790770 | 0.79 | CTSL (0.48) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL25631052 | 0.79 | TAAR1 (0.47) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL14409096 | 0.79 | AGTR2 (0.46) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL7936553 | 0.79 | AGTR2 (0.43) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL7925960 | 0.79 | AGTR2 (0.46) | TSHRCTSLCTSBCTSKLMNA | |
| SCHEMBL1928095 | 0.79 | TSHR (0.58) | TSHRCTSLCTSBCTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994019023-A1 | CYCLOBUTYL ANTISENSE OLIGONUCLEOTIDES, METHODS OF MAKING AND USE THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 1994-09-01 | — | — | WO | disclosed |