Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929351 | 0.89 | ENPP2 (0.39) | FAAHCNR2CNR1TRPV6MEN1 | |
| SCHEMBL1914258 | 0.88 | FAAH (0.45) | FAAHCNR2CNR1TRPV6MEN1 | |
| SCHEMBL7932567 | 0.83 | TRPV6 (0.43) | FAAHCNR2CNR1TRPV6MEN1 | |
| SCHEMBL8688173 | 0.81 | TRPV6 (0.41) | FAAHCNR2CNR1TRPV6MEN1 | |
| SCHEMBL7920649 | 0.80 | CNR2 (0.39) | FAAHCNR2CNR1MEN1KMT2A | |
| SCHEMBL7518648 | 0.79 | MEN1 (0.64) | FAAHCNR2CNR1MEN1KMT2A | |
| SCHEMBL8457462 | 0.79 | HIF1A (0.47) | FAAHCNR2CNR1MEN1KMT2A | |
| SCHEMBL1914007 | 0.79 | FAAH (0.40) | FAAHCNR2CNR1TRPV6MEN1 | |
| SCHEMBL1914146 | 0.79 | LIPE (0.47) | FAAHCNR2CNR1TRPV6MEN1 | |
| SCHEMBL7920787 | 0.78 | IKBKB (0.49) | MEN1KMT2AHIF1AS1PR1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225328-B1 | FOR THERAPY OF DISORDERS OR AILMENTS RELATED TO AN OVERREGULATION OF RETINOIC ACID RECEPTORS AND/OR TO HYPERVIAMINOSIS A | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (FR) | 2001-05-01 | — | — | US | disclosed |
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | disclosed |
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | disclosed |