Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.51 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829434 | 0.79 | RARB (0.67) | HSD11B1RARBSMN1; SMN2CA2HTR2A | |
| SCHEMBL5551587 | 0.79 | RARB (0.67) | HSD11B1RARBSMN1; SMN2CA2HTR2A | |
| SCHEMBL4621460 | 0.78 | SKP2 (0.56) | HSD11B1SKP2RARBSMN1; SMN2CA2 | |
| SCHEMBL13863905 | 0.78 | HSD11B1 (0.45) | HSD11B1SKP2RARBSMN1; SMN2CA2 | |
| SCHEMBL4908052 | 0.78 | HSD11B1 (0.45) | HSD11B1SKP2RARBSMN1; SMN2CA2 | |
| SCHEMBL28900119 | 0.77 | RARB (0.64) | HSD11B1RARBSMN1; SMN2CA2HTR2A | |
| SCHEMBL6934071 | 0.77 | RARB (0.52) | HSD11B1RARBSMN1; SMN2HTR2ARAB9A | |
| SCHEMBL10042906 | 0.76 | SKP2 (0.42) | HSD11B1SKP2RARBCA2RAB9A | |
| SCHEMBL28025514 | 0.76 | RARB (0.51) | RARBHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL83869 | 0.76 | CA2 (0.65) | SKP2RARBSMN1; SMN2CA2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097158-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |