Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27940784 | 0.80 | MEN1 (0.52) | RARBMEN1MAPTKMT2ANR1I2 | |
| SCHEMBL27940858 | 0.80 | HRH3 (0.48) | ALDH1A1HPGDHSD17B10MAPTHDAC6 | |
| SCHEMBL27547212 | 0.79 | LMNA (0.44) | MEN1MAPTKMT2ALTB4R2NR1I2 | |
| SCHEMBL7502664 | 0.79 | ALDH1A1 (0.47) | RARBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL27892575 | 0.77 | RARB (0.51) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL15750344 | 0.77 | RARB (0.72) | RARBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7926844 | 0.76 | HSD11B1 (0.51) | RARBALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL2972655 | 0.76 | LMNA (0.50) | ALDH1A1HPGDHSD17B10MEN1MAPT | |
| SCHEMBL7729718 | 0.76 | MCL1 (0.58) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL4160309 | 0.75 | HNF4A (0.59) | RARBRARADHODHAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103739513-B | 4-methoxyl group-1,3-phenyl-diformyl aminated compounds and application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2015-09-23 | — | — | CN | disclosed |
| CN-103739513-B | 4-methoxyl group-1,3-phenyl-diformyl aminated compounds and application thereof | TIANJIN UNIVERSITY OF TECHNOLOGY (CN) | 2015-09-23 | — | — | CN | disclosed |