Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930108 | 0.80 | KMT2A (0.57) | MEN1KMT2ATDP1ROCK2ROCK1 | |
| SCHEMBL7920931 | 0.78 | TP53 (0.42) | MAPTROCK2ROCK1 | |
| SCHEMBL7930156 | 0.74 | HPGD (0.57) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7929603 | 0.74 | SMYD3 (0.45) | MAPTSMN1; SMN2CYP1A2CYP2C19ROCK2 | |
| SCHEMBL7928025 | 0.71 | SMPD1 (0.56) | MEN1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL553819 | 0.69 | MEN1 (0.54) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL8910176 | 0.69 | TDP1 (0.53) | MEN1KMT2AMAPTTDP1ROCK2 | |
| SCHEMBL11818791 | 0.67 | KMT2A (0.52) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7930170 | 0.66 | NR1H2 (0.43) | — | |
| SCHEMBL30622485 | 0.65 | KDM4E (0.55) | ALDH1A1MEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |