Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930108 | 0.83 | KMT2A (0.57) | KMT2AMEN1LMNAMAPK1NPC1 | |
| SCHEMBL7928025 | 0.76 | SMPD1 (0.56) | HPGDNPSR1KMT2AMEN1MAPT | |
| SCHEMBL7927749 | 0.74 | ALDH1A1 (0.57) | HPGDNPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7920931 | 0.73 | TP53 (0.42) | MAPTHDAC8HDAC6 | |
| SCHEMBL7929603 | 0.73 | SMYD3 (0.45) | MAPTSMN1; SMN2LMNAPOLBHDAC1 | |
| SCHEMBL4628473 | 0.72 | MAPT (0.56) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11818791 | 0.71 | KMT2A (0.52) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4628483 | 0.71 | SCN2A (0.73) | HPGDALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29236663 | 0.71 | MAPT (0.60) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2920246 | 0.71 | MAPK1 (0.65) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |