SCHEMBL7927191

SCHEMBL7927191

COc1ccccc1Nc1ccc2c(c1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.51
PIM1 P11309 1/20 0.51
MAPK14 Q16539 2/20 0.51
MAPT P10636 9/20 0.49
MAPK1 P28482 5/20 0.49
L3MBTL1 Q9Y468 4/20 0.49
POLB P06746 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ALDH1A1 P00352 3/20 0.47
MCL1 Q07820 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
ATM Q13315 1/20 0.47
CASP3 P42574 2/20 0.47
CASP2 P42575 1/20 0.47
CASP7 P55210 1/20 0.47
CASP6 P55212 1/20 0.47
CASP8 Q14790 1/20 0.47
P2RY4 P51582 3/20 0.46
P2RY2 P41231 2/20 0.46
MET P08581 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928231 0.81 MEN1 (0.53) EGFRPIM1MAPK14MAPTMAPK1
SCHEMBL7928282 0.79 APP (0.56) EGFRPIM1MAPK14MAPTMAPK1
SCHEMBL8771240 0.78 EGFR (0.55) EGFRPIM1MAPTMAPK1L3MBTL1
SCHEMBL7930873 0.78 MEN1 (0.56) MAPK14MAPTMAPK1L3MBTL1POLB
SCHEMBL7921433 0.77 MEN1 (0.45) MAPTMAPK1L3MBTL1POLBKDM4E
SCHEMBL7929792 0.76 MAPT (0.57) MAPK14MAPTMAPK1L3MBTL1POLB
SCHEMBL7933112 0.75 EGFR (0.51) EGFRPIM1MAPTMAPK1L3MBTL1
SCHEMBL10658788 0.74 MAPT (0.63) EGFRMAPTMAPK1L3MBTL1POLB
SCHEMBL8618796 0.73 MAPT (0.65) MAPTMAPK1L3MBTL1POLBKDM4E
SCHEMBL7933233 0.73 DHODH (0.47) EGFRPIM1MAPTMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed