Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501725 | 0.80 | KMT2A (0.66) | KMT2AALDH1A1SMN1; SMN2GAANPSR1 | |
| SCHEMBL6500734 | 0.79 | KMT2A (0.49) | KMT2AALDH1A1POLBSMN1; SMN2NPSR1 | |
| SCHEMBL2332909 | 0.79 | KMT2A (0.49) | KMT2AALDH1A1POLBGAANPSR1 | |
| SCHEMBL7928510 | 0.74 | LMNA (0.50) | MMP1TSHRALDH1A1SMN1; SMN2MMP9 | |
| SCHEMBL7924925 | 0.71 | MMP1 (0.48) | MMP1ALDH1A1POLBSMN1; SMN2MMP9 | |
| SCHEMBL7924934 | 0.69 | MMP1 (0.46) | MMP1MMP9MMP2 | |
| SCHEMBL7412217 | 0.69 | KMT2A (0.64) | MMP1TSHRKMT2AALDH1A1POLB | |
| SCHEMBL6797285 | 0.68 | MEN1 (0.43) | KMT2AALDH1A1POLBSMN1; SMN2MMP9 | |
| SCHEMBL7362026 | 0.67 | POLB (0.57) | TSHRKMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL19777756 | 0.66 | POLB (0.57) | KMT2AALDH1A1POLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |