Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.48 |
| ▸ | MMP9 | P14780 | 13/20 | 0.38 |
| ▸ | MMP2 | P08253 | 12/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924930 | 0.88 | MMP1 (0.37) | MMP1MMP9MMP13SMN1; SMN2 | |
| SCHEMBL7360052 | 0.77 | SMN1; SMN2 (0.47) | MMP1MMP9MMP2MMP13SMN1; SMN2 | |
| SCHEMBL7924934 | 0.76 | MMP1 (0.46) | MMP1MMP9MMP2 | |
| SCHEMBL7928511 | 0.71 | MMP1 (0.51) | MMP1MMP9MMP2MMP13SMN1; SMN2 | |
| SCHEMBL7447099 | 0.68 | MMP1 (0.52) | MMP1MMP9MMP2MMP13SMN1; SMN2 | |
| SCHEMBL6338957 | 0.66 | MMP1 (0.53) | MMP1MMP9MMP2MMP13SMN1; SMN2 | |
| SCHEMBL1656016 | 0.64 | MMP1 (0.50) | MMP1MMP9MMP2MMP13SMN1; SMN2 | |
| SCHEMBL7924869 | 0.63 | SMN1; SMN2 (0.60) | MMP1MMP9MMP13SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4027206 | 0.62 | MMP1 (0.49) | MMP1MMP9MMP2MMP13SMN1; SMN2 | |
| SCHEMBL7512941 | 0.62 | PTGS2 (0.55) | MMP1MMP9MMP2MMP13SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |