Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | RNF4 | P78317 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 6/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | KLK1 | P06870 | 2/20 | 0.43 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938155 | 0.91 | MTNR1B (0.50) | PLAURNF4MTNR1AMTNR1BPLG | |
| SCHEMBL7940421 | 0.89 | KDR (0.48) | PLAUKDRMTNR1AMTNR1BPLG | |
| SCHEMBL7937755 | 0.89 | FGFR1 (0.44) | PLAURNF4KDRMTNR1AMTNR1B | |
| SCHEMBL7940489 | 0.88 | MTNR1A (0.48) | PLAUKDRMTNR1AMTNR1BLMNA | |
| SCHEMBL7928941 | 0.84 | RNF4 (0.51) | PLAURNF4MTNR1AMTNR1BPLG | |
| SCHEMBL7928850 | 0.83 | KDR (0.63) | KDR | |
| SCHEMBL7940509 | 0.81 | MTNR1B (0.50) | PLAUMTNR1AMTNR1BPLGKLK1 | |
| SCHEMBL7937751 | 0.79 | KMT2A (0.47) | KDRMTNR1AMTNR1BLMNAL3MBTL1 | |
| SCHEMBL7938151 | 0.79 | PLAU (0.42) | PLAUKDRMTNR1AMTNR1BPLG | |
| SCHEMBL8497579 | 0.78 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835868-B1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | LILLY CO ELI (US) | 2001-08-29 | — | — | EP | disclosed |
| US-5929090-A | NOVEL COMPOUNDS FOR TREATING ESTROGEN DEPRIVATION CAUSED BY MENOPAUSE OR OVARIECTOMY; TREATING OSTEOPOROSIS, CARDIOVASCULAR DISEASES, AND ENDOMETRIOSIS | ELI LILLY AND COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0835868-A1 | 2-Aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |