Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690177 | 0.68 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL4256305 | 0.67 | CA12 (0.44) | ALDH1A1MAPT | |
| SCHEMBL4264227 | 0.67 | CA1 (0.35) | — | |
| SCHEMBL7922717 | 0.64 | AR (0.32) | MAPT | |
| SCHEMBL15958871 | 0.62 | TRPV4 (0.42) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL4257927 | 0.61 | ABCC8 (0.49) | ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL27614015 | 0.60 | CYP11B1 (0.40) | — | |
| SCHEMBL7932691 | 0.60 | — | — | |
| SCHEMBL28994625 | 0.60 | TRPV4 (0.54) | ALDH1A1MAPTHPGD | |
| SCHEMBL16327958 | 0.57 | PDE2A (0.41) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | claimed |
| US-6232310-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-05-15 | — | — | US | disclosed |