Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059189 | 0.89 | ALOX15 (0.44) | KDM4EHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL6197535 | 0.87 | LMNA (0.42) | KDM4EHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL1132630 | 0.85 | KDM4E (0.37) | KDM4EHPGDALDH1A1HSD17B10KMT2A | |
| SCHEMBL28938014 | 0.82 | CLCN2 (0.42) | KDM4EHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL3252726 | 0.82 | HTT (0.46) | KDM4EHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL30689781 | 0.82 | HTT (0.46) | KDM4EHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL17205759 | 0.81 | KDM4E (0.37) | KDM4EHPGDALDH1A1HSD17B10MYC | |
| SCHEMBL27860915 | 0.79 | ALDH1A1 (0.60) | KDM4EHPGDALDH1A1HSD17B10MYC | |
| SCHEMBL5323103 | 0.78 | KDM4E (0.55) | KDM4EHPGDALDH1A1HSD17B10MYC | |
| SCHEMBL9857877 | 0.78 | ALDH1A1 (0.58) | KDM4EHPGDALDH1A1HSD17B10MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879814-B1 | Triaromatic compounds, compositions containing them and uses thereof | CT INTERNAT DE BR RECH S DERMA (FR) | 2001-11-28 | — | — | EP | disclosed |
| EP-0879814-A1 | Triaromatic compounds, compositions containing them and uses thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-11-25 | — | — | EP | disclosed |