Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571254 | 0.86 | GABRA1 (0.42) | GABRA1GABRB2DRD2HTR1DDRD3 | |
| SCHEMBL14059189 | 0.86 | ALOX15 (0.44) | ALOX15MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL28776561 | 0.82 | CLCN2 (0.44) | CLCN2MRGPRX4ALOX15MAPK1KDM4E | |
| SCHEMBL7929322 | 0.82 | KDM4E (0.55) | MRGPRX4ALOX15MAPK1KDM4EALDH1A1 | |
| SCHEMBL7569500 | 0.80 | GABRA1 (0.37) | GABRA1GABRB2DRD2HTR1DDRD3 | |
| SCHEMBL3252726 | 0.79 | HTT (0.46) | ALOX15MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL30689781 | 0.79 | HTT (0.46) | ALOX15MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL28032046 | 0.77 | CLCN2 (0.51) | CLCN2MRGPRX4ALOX15MAPK1KDM4E | |
| SCHEMBL5640187 | 0.77 | KDM4E (0.34) | MRGPRX4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5640607 | 0.77 | ALDH1A1 (0.42) | MRGPRX4KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341145-A | Chemical compound | 博拉公司 | 2022-04-12 | — | — | CN | disclosed |