Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69776 | 0.80 | TTR (0.56) | TTRHPGDHSD17B10ALBMAPK1 | |
| SCHEMBL12817414 | 0.75 | TTR (0.50) | TTRHPGDHSD17B10ALBMAPK1 | |
| SCHEMBL1043966 | 0.73 | TP53 (0.45) | TTRHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL28263560 | 0.73 | TP53 (0.38) | TTRHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL8410940 | 0.72 | TTR (0.48) | TTRHPGDHSD17B10ALBMAPK1 | |
| SCHEMBL7926703 | 0.69 | TTR (0.58) | TTRHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL6720850 | 0.69 | TTR (0.50) | TTRHPGDHSD17B10ALBMAPK1 | |
| SCHEMBL7930045 | 0.68 | TTR (0.50) | TTRHPGDHSD17B10ALBMAPK1 | |
| SCHEMBL7932602 | 0.68 | TTR (0.43) | TTRHPGDHSD17B10TSHRALB | |
| SCHEMBL7929422 | 0.68 | TTR (0.50) | TTRHPGDHSD17B10ALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707849-B1 | USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S L (ES) | 2001-12-19 | — | — | EP | disclosed |
| EP-0707849-A1 | USE OF DERIVATIVES OF 2,4-BISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S.L. (ES) | 1996-04-24 | — | — | EP | disclosed |