Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69776 | 0.80 | TTR (0.56) | TTRMAPK14CHEK1DAPK3RET | |
| SCHEMBL8410940 | 0.78 | TTR (0.48) | TTRMAPK14CHEK1DAPK3RET | |
| SCHEMBL12817414 | 0.75 | TTR (0.50) | TTRMAPK14CHEK1DAPK3RET | |
| SCHEMBL7929465 | 0.70 | CRHBP (0.42) | TTRMAPK14TDP1MEN1LMNA | |
| SCHEMBL5988354 | 0.69 | TTR (0.58) | TTRMAPK14CHEK1DAPK3RET | |
| SCHEMBL6720850 | 0.69 | TTR (0.50) | TTRMAPK14CHEK1DAPK3RET | |
| SCHEMBL29386792 | 0.69 | MAPK1 (0.47) | TTRTDP1CA1CA2CA4 | |
| SCHEMBL126187 | 0.69 | MAPK1 (0.47) | TTRTDP1CA1CA2CA4 | |
| SCHEMBL7930045 | 0.68 | TTR (0.50) | TTRMAPK14CHEK1DAPK3RET | |
| SCHEMBL7929410 | 0.68 | TTR (0.43) | TTRMAPK14CHEK1DAPK3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707849-B1 | USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S L (ES) | 2001-12-19 | — | — | EP | disclosed |
| US-5248432-A | Flotation fluids for gyroscopes and accelerometers | CHARLES STARK DRAPER LABORATORY, INC. (US) | 1993-09-28 | — | — | US | disclosed |
| US-5177252-A | High density flotation fluids and lubricants for inertial instruments | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 1993-01-05 | — | — | US | disclosed |
| US-4835304-A | FLOTATION FLUIDS FOR INERTIAL INSTRUMENTS SUCH AS GYROSCOPESAD ACCELEROMETERS; HIGH VISCOSITY; HYDRAULIC FLUIDS | CHARLES STARK DRAPER LABORATORY (US) | 1989-05-30 | — | — | US | disclosed |