SCHEMBL7929822

SCHEMBL7929822

C=CNC(=O)CCc1ccc(CCC(=O)NC=C)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 7/20 0.50
HDAC2 Q92769 5/20 0.47
HDAC8 Q9BY41 5/20 0.47
HDAC6 Q9UBN7 4/20 0.47
MAPT P10636 2/20 0.44
HTT P42858 1/20 0.44
ALDH1A1 P00352 2/20 0.43
HDAC3 O15379 3/20 0.41
HDAC4 P56524 3/20 0.41
HDAC7 Q8WUI4 3/20 0.41
HDAC10 Q969S8 3/20 0.41
HDAC11 Q96DB2 3/20 0.41
HDAC9 Q9UKV0 3/20 0.41
HDAC5 Q9UQL6 3/20 0.41
POLB P06746 1/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
FFAR1 O14842 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929831 0.85 GAA (0.47) HDAC1HDAC2HDAC8HDAC6MAPT
SCHEMBL28402134 0.80 PLAAT3 (0.45) HDAC1HDAC2HDAC8HDAC6ALDH1A1
SCHEMBL7929809 0.78 LMNA (0.44) HDAC8HDAC6HTTALDH1A1POLB
SCHEMBL13310793 0.72 THRB (0.50) HDAC1HDAC2HDAC8HDAC6HDAC3
SCHEMBL14855545 0.72 HDAC2 (0.63) HDAC1HDAC2HDAC8HDAC6MAPT
SCHEMBL14387746 0.71 HDAC1 (0.53) HDAC1HDAC2HDAC8HDAC6MAPT
SCHEMBL22238139 0.71 HDAC2 (0.43) HDAC2HDAC8MAPTALDH1A1POLB
SCHEMBL10284708 0.71 GAA (0.58) HTTALDH1A1GAA
SCHEMBL29158015 0.70 TSHR (0.50) HDAC1HDAC2HDAC8HDAC6MAPT
SCHEMBL8440530 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473881-B1 Liquid absorption agent SHOWA DENKO KK (JP) 2001-11-07 EP disclosed
US-5788950-A Method for the synthesis of mixed metal oxide powders SHOWA DENKO K.K. (JP) 1998-08-04 US disclosed
US-5744118-A MIXING ABSORBENT RESIN AND METAL SALTS, SWELLING AND GELATION, ADJUSTMENT OF PH, PYROLYSIS AND ROASTING SHOWA DENKO K.K. (JP) 1998-04-28 US disclosed
EP-0510246-B1 Use of fine particulate crosslinked type n-vinylamide resin microgel SHOWA DENKO KK (JP) 1996-09-25 EP disclosed
US-5407996-A Contacting with an aqueous solution of metal ion or metal oxide to form a gel; calcining SHOWA DENKO K.K. (JP) 1995-04-18 US disclosed
US-5338815-A Used in thickeners, dispersion stabilizers and lubricants SHOWA DENKO K.K. (JP) 1994-08-16 US disclosed
US-5300606-A Crosslinked N-vinylamide resin SHOWA DENKO K.K. (JP) 1994-04-05 US disclosed
US-5280095-A N-vinylcarboxylic acid amine resin SHOWA DENKO K.K. (JP) 1994-01-18 US disclosed
EP-0510246-A1 Use of fine particulate crosslinked type n-vinylamide resin microgel SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-10-28 EP disclosed
EP-0473881-A1 Liquid absorption agent SHOWA DENKO KABUSHIKI KAISHA (JP) 1992-03-11 EP disclosed