Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9892899 | 0.85 | SMN1; SMN2 (1.00) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12354954 | 0.83 | POLB (0.68) | MEN1CYP1A2KMT2ASMN1; SMN2POLB | |
| SCHEMBL11515168 | 0.83 | MEN1 (0.73) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6375789 | 0.80 | MEN1 (0.68) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11518015 | 0.80 | MEN1 (0.68) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3807415 | 0.79 | SMN1; SMN2 (0.67) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9892978 | 0.79 | SMN1; SMN2 (0.67) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9891528 | 0.77 | KMT2A (0.65) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28676132 | 0.77 | SMN1; SMN2 (0.65) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11188939 | 0.76 | SMN1; SMN2 (0.63) | MEN1CYP1A2KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190285-A1 | METHODS OF TREATING A BOTULINUM TOXIN RELATED CONDITION IN A SUBJECT | ABSOLUTE SCIENCE, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| US-20110034521-A1 | COMPOUNDS AND METHODS FOR TREATING ZINC MATRIX METALLOPROTEASE DEPENDENT DISEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-10 | — | — | US | disclosed |
| WO-2010033360-A1 | METHODS OF TREATING A BOTULINUM TOXIN RELATED CONDITION IN A SUBJECT | 1/3 ABSOLUTE SCIENCE, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034521-A1 | COMPOUNDS AND METHODS FOR TREATING ZINC MATRIX METALLOPROTEASE DEPENDENT DISEASES | MMP7, MMP3, MMP9 | MEN1 938/4885CYP1A2 1547/4885KMT2A 799/4885 |
| US-20110190285-A1 | METHODS OF TREATING A BOTULINUM TOXIN RELATED CONDITION IN A SUBJECT | NPY5R, RAC3, CPA3 | MEN1 1392/4885CYP1A2 927/4885KMT2A 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.