Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933295 | 0.96 | ADAMTS5 (0.39) | ADAMTS5FAAH | |
| SCHEMBL7930657 | 0.92 | ADAMTS5 (0.43) | ADAMTS5CCNE2CCNE1CDK2CXCR2 | |
| SCHEMBL7921285 | 0.91 | ADAMTS5 (0.40) | ADAMTS5FAAHTSHRMEN1NPC1 | |
| SCHEMBL7927279 | 0.89 | ADAMTS5 (0.44) | ADAMTS5FAAHMEN1NPC1ALDH1A1 | |
| SCHEMBL7930019 | 0.88 | ADAMTS5 (0.46) | ADAMTS5FAAHNPC1RAB9A | |
| SCHEMBL7921278 | 0.88 | ADAMTS5 (0.42) | ADAMTS5CXCR2TSHRRECQLMEN1 | |
| SCHEMBL7929940 | 0.87 | ELANE (0.34) | ADAMTS5CCNE2CCNE1CDK2FAAH | |
| SCHEMBL7927144 | 0.85 | ELANE (0.35) | ADAMTS5CCNE2CCNE1CDK2FAAH | |
| SCHEMBL7927126 | 0.85 | ADAMTS5 (0.43) | ADAMTS5FAAHTSHRRECQLMEN1 | |
| SCHEMBL7928272 | 0.84 | ELANE (0.34) | RECQLMEN1NPC1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661350-B1 | Quinizarin compound, method for production thereof, and use therefor | NIPPON CATALYTIC CHEM IND (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5817843-A | Quinizarin compound, method for production thereof, and use therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5608091-A | SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0661350-A1 | Quinizarin compound, method for production thereof, and use therefor | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |