SCHEMBL7933295

SCHEMBL7933295

CCCCCCCCOc1c(Nc2ccccc2)c(Nc2ccccc2)c(F)c2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADAMTS5 Q9UNA0 2/20 0.39
FAAH O00519 12/20 0.36
CDC25B P30305 1/20 0.35
CNR2 P34972 2/20 0.35
SMPD1 P17405 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930029 0.96 ADAMTS5 (0.43) ADAMTS5FAAH
SCHEMBL7930019 0.90 ADAMTS5 (0.46) ADAMTS5FAAHCDC25B
SCHEMBL7930657 0.88 ADAMTS5 (0.43) ADAMTS5FAAH
SCHEMBL7929762 0.87 SMPD1 (0.35) FAAHSMPD1
SCHEMBL7933215 0.87 FAAH (0.38) FAAHCNR2SMPD1
SCHEMBL7921285 0.87 ADAMTS5 (0.40) ADAMTS5FAAHCNR2
SCHEMBL7930360 0.86 ELANE (0.37) FAAHCNR2SMPD1
SCHEMBL7928353 0.86 ELANE (0.35) FAAHCNR2SMPD1
SCHEMBL7921275 0.86 ADAMTS5 (0.42) ADAMTS5FAAHCDC25B
SCHEMBL7928316 0.85 ELANE (0.34) FAAHCDC25BCNR2SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed