Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.56 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.56 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18746058 | 0.93 | CHEK1 (0.50) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL6837400 | 0.89 | CA2 (0.48) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL7783812 | 0.83 | CHEK1 (0.75) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL3067980 | 0.83 | CHEK1 (0.56) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL9622193 | 0.83 | GABRA1 (0.50) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL15781534 | 0.82 | CYP2C19 (0.46) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL888409 | 0.82 | CYP2C19 (0.46) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL875823 | 0.82 | ERN1 (0.58) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL18544652 | 0.81 | CHEK1 (0.72) | CHEK1DAPK3RETPDGFRBPIM1 | |
| SCHEMBL18855386 | 0.81 | CHEK1 (0.54) | CHEK1DAPK3RETPDGFRBPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745365-B | Metallocene-containing phenol metal complex and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-112745405-B | Catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-112745444-B | Olefin polymerization reaction and olefin polymer | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-112745444-A | Olefin polymerization reaction and olefin polymer | 中国石油化工股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-112745405-A | Catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-112745365-A | Metallocene-containing phenol metal complex and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| US-10551739-B2 | Resist composition, and resist film, pattern forming method, and method for manufacturing electronic device, each using resist composition | FUJIFILM CORPORATION (JP) | 2020-02-04 | — | — | US | disclosed |
| US-10444627-B2 | Pattern formation method, active light-sensitive or radiation-sensitive resin composition, resist film, production method for electronic device using same, and electronic device | FUJIFILM CORPORATION (JP) | 2019-10-15 | — | — | US | disclosed |
| US-10324374-B2 | Active light sensitive or radiation sensitive resin composition, active light sensitive or radiation sensitive film, mask blank provided with active light sensitive or radiation sensitive film, pattern forming method, method for manufacturing electronic device, electronic device and novel compound | FUJIFILM CORPORATION (JP) | 2019-06-18 | — | — | US | disclosed |
| US-20180210339-A1 | RESIST COMPOSITION, AND RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE, EACH USING RESIST COMPOSITION | FUJIFILM CORPORATION (JP) | 2018-07-26 | — | — | US | disclosed |
| US-9718901-B2 | Resin composition and pattern forming method using the same | FUJIFILM CORPORATION (JP) | 2017-08-01 | — | — | US | disclosed |
| US-20170146908-A1 | PATTERN FORMING METHOD AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE USING SAME | FUJIFILM CORPORATION (JP) | 2017-05-25 | — | — | US | disclosed |
| US-9632222-B2 | Method for manufacturing a color filter, color filter and solid-state imaging device | FUJIFILM CORPORATION (JP) | 2017-04-25 | — | — | US | disclosed |
| US-20170059990-A1 | RADIATION-SENSITIVE OR ACTINIC RAY-SENSITIVE RESIN COMPOSITION, RESIST FILM USING THE SAME, MASK BLANK, RESIST PATTERN FORMING METHOD, ELECTRONIC DEVICE MANUFACTURING METHOD, AND ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2017-03-02 | — | — | US | disclosed |
| US-20170054076-A1 | SEMICONDUCTOR DEVICE AND INSULATING LAYER-FORMING COMPOSITION | FUJIFILM CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |
| US-20080287371-A1 | MACROCYCLIC ANTAGONISTS OF THE MOTILIN RECEPTOR FOR MODULATION OF THE MIGRATING MOTOR COMPLEX | TRANZYME PHARMA INC. | 2008-11-20 | — | — | US | disclosed |
| US-20040082578-A1 | Arylindenopyridines and related therapeutic and prophylactic methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-04-29 | — | — | US | disclosed |
| US-20040082578-A1 | Arylindenopyridines and related therapeutic and prophylactic methods | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-04-29 | — | — | US | disclosed |
| EP-0707849-B1 | USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S L (ES) | 2001-12-19 | — | — | EP | disclosed |
| EP-0707849-A1 | USE OF DERIVATIVES OF 2,4-BISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S.L. (ES) | 1996-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082578-A1 | Arylindenopyridines and related therapeutic and prophylactic methods | ADORA2A, ADORA1, PDE2A | CHEK1 3618/4885DAPK3 3035/4885RET 2242/4885 |
| US-10324374-B2 | Active light sensitive or radiation sensitive resin composition, active light sensitive or radiation sensitive film, mask blank provided with active light sensitive or radiation sensitive film, pattern forming method, method for manufacturing electronic device, electronic device and novel compound | ERCC1, RER1, ECPAS | CHEK1 731/4885DAPK3 3053/4885RET 3143/4885 |
| US-20080287371-A1 | MACROCYCLIC ANTAGONISTS OF THE MOTILIN RECEPTOR FOR MODULATION OF THE MIGRATING MOTOR COMPLEX | MLNR, CCKAR, CCKBR | CHEK1 126/4885DAPK3 3240/4885RET 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.