SCHEMBL7930742

SCHEMBL7930742

CCCCCCCCC1CCc2c(cc(F)c(B(O)O)c2F)C1(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7935001 1.00 DRD2 (0.31) DRD2DRD3
SCHEMBL5722637 0.83 DRD2 (0.33) DRD2DRD3
SCHEMBL7792870 0.74 CYP3A4 (0.40) DRD2DRD3
SCHEMBL7793326 0.74 CYP3A4 (0.40) DRD2DRD3
SCHEMBL7930592 0.74 LTA4H (0.35)
SCHEMBL7922786 0.73 NAAA (0.35)
SCHEMBL7668090 0.72 GAA (0.33)
SCHEMBL5722723 0.72 LTA4H (0.35)
SCHEMBL7935198 0.69
SCHEMBL5722701 0.68 RARB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944690-B1 1,1,5,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES AVENTIS RES & TECH GMBH & CO (DE) 2001-11-28 EP disclosed
EP-0944690-A1 1,1,5,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES Aventis Research & Technologies GmbH & Co KG (DE) 1999-09-29 EP disclosed
WO-1998027179-A1 1,1,5,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-06-25 WO disclosed