Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 4/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722723 | 0.92 | LTA4H (0.35) | LTA4HRARBCRBNRARANR5A1 | |
| SCHEMBL7922659 | 0.87 | CYP3A4 (0.31) | — | |
| SCHEMBL5722783 | 0.79 | ESR2 (0.33) | — | |
| SCHEMBL8462778 | 0.78 | THRA (0.46) | LTA4HRARBCRBNRARAPRKAB2 | |
| SCHEMBL7792455 | 0.78 | HTR1D (0.37) | LTA4HRARBRARANR5A1HTR1D | |
| SCHEMBL7930742 | 0.74 | DRD2 (0.31) | — | |
| SCHEMBL7935212 | 0.73 | NR5A1 (0.40) | LTA4HCRBNNR5A1LMNACNR2 | |
| SCHEMBL5722671 | 0.72 | HTR1D (0.37) | LTA4HRARBRARANR5A1HTR1D | |
| SCHEMBL5722695 | 0.72 | CRBN (0.40) | LTA4HCRBNNR5A1HTR1DHTR1B | |
| SCHEMBL5722700 | 0.72 | NR5A1 (0.40) | LTA4HCRBNNR5A1LMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944690-B1 | 1,1,5,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-11-28 | — | — | EP | disclosed |