SCHEMBL7930862

SCHEMBL7930862

O=C(O)c1cccc2c1C(=O)[N]C2=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
MAPT P10636 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
LMNA P02545 1/20 0.55
HNF4A P41235 1/20 0.52
MYC P01106 1/20 0.46
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 2/20 0.45
POLB P06746 1/20 0.45
LIG1 P18858 1/20 0.43
ALOX15 P16050 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
GFER P55789 1/20 0.41
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10555860 0.83 HNF4A (0.38) ALDH1A1MAPTL3MBTL1LMNAHNF4A
SCHEMBL946184 0.83 PDK2 (0.43) ALDH1A1MAPTL3MBTL1LMNAHNF4A
SCHEMBL7026836 0.83 HNF4A (0.38) ALDH1A1MAPTL3MBTL1LMNAHNF4A
SCHEMBL2763213 0.83 KEAP1 (0.56) ALDH1A1MAPTHNF4AHSD17B10KDM4E
SCHEMBL70265 0.77 ALDH1A1 (0.63) ALDH1A1MAPTL3MBTL1LMNAHNF4A
SCHEMBL69716 0.77 ALDH1A1 (0.69) ALDH1A1MAPTL3MBTL1LMNAHNF4A
SCHEMBL5866519 0.75 ALDH1A1 (0.81) ALDH1A1MAPTL3MBTL1LMNAHNF4A
SCHEMBL69132 0.75 ALDH1A1 (0.88) ALDH1A1MAPTL3MBTL1LMNAHNF4A
SCHEMBL10621855 0.74 HDAC4 (0.47) ALDH1A1MAPTLMNAHNF4AHSD17B10
SCHEMBL7222595 0.74 ADORA2A (0.50) ALDH1A1MAPTL3MBTL1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1093512-A2 METHODS FOR REDUCING OR PREVENTING THE DEGRADATION OF RUBBER IN DOMESTIC BLEACH PROCESSES The Procter & Gamble Company (US) 2001-04-25 EP disclosed
WO-2000003369-A2 METHODS FOR REDUCING OR PREVENTING THE DEGRADATION OF RUBBER IN DOMESTIC BLEACH PROCESSES THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO disclosed
EP-0405135-B1 Reactively capped polyarylene sulfides and method and intermediates for their preparation GEN ELECTRIC (US) 1995-01-18 EP disclosed
US-5122578-A Copolymers prepared by melt blending polyphenylene ethers containing epoxy groups with polyarylene sulfides containing reactive functional groups GENERAL ELECTRIC COMPANY (US) 1992-06-16 US disclosed
EP-0452705-A2 Polyphenylene ether-polyarylene sulfide compositions GENERAL ELECTRIC COMPANY (US) 1991-10-23 EP disclosed
US-5015703-A Reactively capped polyarylene sulfide and method and intermediates for their preparation GENERAL ELECTRIC COMPANY (US) 1991-05-14 US disclosed
US-5015704-A Reactively capped polyarylene sulfide and method and intermediates for their preparation GENERAL ELECTRIC COMPANY (US) 1991-05-14 US disclosed
EP-0405135-A1 Reactively capped polyarylene sulfides and method and intermediates for their preparation GENERAL ELECTRIC COMPANY (US) 1991-01-02 EP disclosed