SCHEMBL7933227

SCHEMBL7933227

N#Cc1ccc(Nc2c(F)c3c(c(F)c2Nc2ccc(C#N)cc2)C(=O)c2c(O)ccc(O)c2C3=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.46
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
SYK P43405 1/20 0.40
CA12 O43570 3/20 0.38
CA9 Q16790 3/20 0.38
TMPRSS4 Q9NRS4 1/20 0.38
VCP P55072 1/20 0.37
SALL4 Q9UJQ4 1/20 0.36
MMP2 P08253 1/20 0.36
TDO2 P48775 1/20 0.36
TSHR P16473 2/20 0.36
TBXA2R P21731 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
NLRP3 Q96P20 1/20 0.36
TOP2A P11388 1/20 0.35
TOP2B Q02880 1/20 0.35
CA3 P07451 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930796 0.94 CXCR2 (0.44) CXCR2CA2CA1SYKCA12
SCHEMBL7921180 0.83 CXCR2 (0.44) CXCR2CA2CA1CA12SALL4
SCHEMBL6652697 0.82 MAPT (0.44) CXCR2CA2CA1SYKMMP2
SCHEMBL8733582 0.82 TAS1R3 (0.39) CXCR2TMPRSS4SALL4TSHRLMNA
SCHEMBL7930614 0.82 ADAMTS5 (0.40) CXCR2CA2CA1CA12CA9
SCHEMBL7933074 0.80 TBXA2R (0.38) CXCR2TBXA2RHTT
SCHEMBL7930883 0.80 CXCR2 (0.47) CXCR2TSHRLMNAMAPTCYP3A4
SCHEMBL6654379 0.77 MAPT (0.42) CXCR2CA2CA1SYKMMP2
SCHEMBL7921288 0.77 MAPT (0.46) CA2CA1SYKLMNAMAPT
SCHEMBL7928305 0.77 MEN1 (0.42) CA2CA1TSHRMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed