Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783016 | 0.85 | THRB (0.42) | THRBPPARARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7791424 | 0.83 | THRB (0.40) | THRBPPARARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3763325 | 0.81 | THRB (0.65) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL7928857 | 0.80 | TDP1 (0.42) | PPARARAB9ANPC1TSHRALDH1A1 | |
| SCHEMBL7921579 | 0.78 | ALDH1A1 (0.50) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL11517365 | 0.78 | LTA4H (0.44) | THRBPPARATSHRTP53TDP1 | |
| SCHEMBL10338214 | 0.76 | ALOX15 (0.50) | PPARARAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL11714166 | 0.75 | THRB (0.57) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL5999298 | 0.74 | THRB (0.57) | THRBRAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL28331865 | 0.74 | TDP1 (0.60) | THRBRAB9ANPC1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850929-B1 | Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates | ATOFINA CHEM INC (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-0850929-A1 | Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1998-07-01 | — | — | EP | disclosed |