Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066580 | 0.88 | ALDH1A1 (0.48) | TDP1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL5691676 | 0.88 | ALDH1A1 (0.48) | TDP1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL7607961 | 0.85 | MAPT (0.39) | TDP1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL7604074 | 0.82 | WDR5 (0.46) | TDP1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL1930924 | 0.81 | ALDH1A1 (0.43) | TDP1ALDH1A1TSHRMAPTESR1 | |
| SCHEMBL7600324 | 0.81 | WDR5 (0.44) | TDP1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL6681906 | 0.81 | HPGDS (0.45) | TDP1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL5240843 | 0.79 | DNMT1 (0.42) | TDP1ALDH1A1HSD17B10CYP2A6TSHR | |
| Phosphine SCHEMBL28241012 | 0.79 | HPGDS (0.44) | TDP1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL17360625 | 0.79 | GPR55 (0.46) | GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123938-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5604242-A | ALKOXY- AND CARBOXY-SUBSTITUTED PIPERIDINES FOR SUPPRESSING UPTAKE OF GAMMA-AMINOBUTYRIC ACID, ANALGESICS, ANXIOLYTIC OR ANTIEPILEPTIC AGENTS | NOVO NORDISK A/S (DK) | 1997-02-18 | — | — | US | disclosed |
| CN-1128989-A | N-substituted azaheterocylic carboxylic acid and esters thereof | NOVO NORDISK AS (DK) | 1996-08-14 | — | — | CN | disclosed |
| EP-0705248-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-04-10 | — | — | EP | disclosed |
| EP-0672675-A1 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5451649-A | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| WO-1995000486-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1995-01-05 | — | — | WO | disclosed |