Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 11/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8379817 | 0.98 | NOS2 (0.56) | NOS2ADRA1ANISCHADRA2AADRA1D | |
| SCHEMBL7802794 | 0.74 | NOS2 (1.00) | NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL8378309 | 0.72 | NOS2 (0.96) | NOS2NOS1 | |
| SCHEMBL7804437 | 0.72 | NOS2 (0.61) | NOS2NOS1 | |
| SCHEMBL7938376 | 0.71 | NOS2 (0.59) | NOS2NOS1 | |
| SCHEMBL8058362 | 0.71 | NOS3 (0.57) | NOS2ADRA1ANISCHADRA2AADRA1D | |
| Hydrochloric Acid SCHEMBL8380996 | 0.70 | NOS2 (0.58) | NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL8104231 | 0.70 | NOS3 (0.56) | NOS2ADRA1ANISCHADRA2AADRA1D | |
| SCHEMBL11244413 | 0.68 | ADRA1A (0.50) | ADRA1ANISCHADRA2AADRA1DADRA1B | |
| SCHEMBL7806689 | 0.68 | NOS2 (1.00) | NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248745-B1 | MIXTURE COMPRISING A CYCLOOXYGENASE-2 (COX-2) INHIBITOR AND A 1,2-DIHYDRO-4-AMINOQUINAZOLINE DERIVATIVE INHIBITOR OF INDUCED NITRIC OXIDE SYNTHASE (INOS); NON-STEROIDAL ANTIINFLAMMATORY AGENTS | ASTRAZENECA AB (SE) | 2001-06-19 | — | — | US | claimed |