Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923928 | 0.79 | CA1 (0.43) | CA1CA2CA4KMT2ACYP2D6 | |
| SCHEMBL31350077 | 0.75 | — | — | |
| SCHEMBL930707 | 0.73 | CA1 (0.45) | CA1CA2CA4KMT2ACYP2D6 | |
| SCHEMBL10881612 | 0.73 | PSEN1 (0.44) | CA1CA2CA4KMT2ACYP2D6 | |
| SCHEMBL21357944 | 0.71 | ALDH1A1 (0.46) | MAPK1ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL28653429 | 0.70 | ALDH1A1 (0.38) | MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28945735 | 0.68 | CA1 (0.46) | CA1CA2CA4KMT2ACA6 | |
| SCHEMBL11828562 | 0.67 | KMT2A (0.56) | CA1CA2CA4KMT2ACYP2D6 | |
| SCHEMBL4118123 | 0.67 | — | — | |
| SCHEMBL30809938 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316634-B2 | REACTING 3-ALKOXY/HYDROXY-2-HALO-CYCLOHEPTEN-1-ONE WITH ALKYLAMINIDINE HALIDE TO FORM CYCLOHEPTIMIDAZOLE COMPOUND | KOTOBUKI PHARMACEUTICAL CO LTD (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6278027-B1 | AS CHEMICAL INTERMEDIATES IN PREPARATION OF DRUGS SUCH AS CYCLOHEPTIMIDAZOLE DERIVATIVES | KOTOBUKI PHARMACEUTICAL CO LTD (JP) | 2001-08-21 | — | — | US | disclosed |
| US-20010008944-A1 | Method for preparing cycloheptimidazoles | TOMIYAMA TSUYOSHI (JP) | 2001-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008944-A1 | Method for preparing cycloheptimidazoles | DHFR, DHPS, MTHFD1 | CA1 1829/4885CA2 3910/4885CA4 1916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.