SCHEMBL7932439

SCHEMBL7932439

Cc1cccc([C]2C=Cc3ccccc32)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.41
RAB9A P51151 5/20 0.41
NPC1 O15118 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HPGD P15428 2/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
NFKB1 P19838 2/20 0.41
NFKB2 Q00653 2/20 0.41
RELA Q04206 2/20 0.41
MAPT P10636 1/20 0.41
PDK2 Q15119 1/20 0.39
MAOB P27338 1/20 0.38
ADORA1 P30542 2/20 0.38
ENPP3 O14638 1/20 0.38
ADORA2A P29274 1/20 0.38
CNR2 P34972 2/20 0.37
CNR1 P21554 1/20 0.37
CHEK1 O14757 1/20 0.37
MAP4K4 O95819 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8167514 0.79 MEN1 (0.40) ACHERAB9ANPC1SMN1; SMN2HPGD
SCHEMBL217272 0.79 ALDH1A1 (0.43) ACHEHPGDTSHRALDH1A1MAPT
SCHEMBL29213167 0.77 ALDH1A1 (0.41) ACHEHPGDTSHRALDH1A1MAPT
SCHEMBL28414965 0.77 ACHE (0.55) ACHERAB9ANPC1SMN1; SMN2HPGD
SCHEMBL24689747 0.74 ACHE (0.52) ACHERAB9ANPC1SMN1; SMN2HPGD
SCHEMBL6571167 0.74 MAOB (0.40) ACHERAB9ANPC1SMN1; SMN2HPGD
SCHEMBL5921807 0.73 LMNA (0.50) ACHEHPGDTSHRALDH1A1MAPT
SCHEMBL2922149 0.73 RAB9A (0.52) ACHERAB9ANPC1SMN1; SMN2HPGD
SCHEMBL18574523 0.72 RAB9A (0.46) ACHERAB9ANPC1SMN1; SMN2HPGD
SCHEMBL29281380 0.72 ALDH1A1 (0.38) ACHEHPGDTSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6187889-B1 COPOLYMER OF AN ALPHA-OLEFIN WITH AN ALKENYL AROMATIC HYDROCARBON, HAVING A STRUCTURE AT WHICH TERTIARY CARBON ATOMS ARE MUTUALLY SEPARATED BY TWO METHYLENE GROUPS IN THE BACKBONE OF THE COPOLYMER; STRETCHING, WRAPPING FILMS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-13 US disclosed
EP-0970964-A2 Method for producing titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-01-12 EP disclosed