SCHEMBL7932452

SCHEMBL7932452

CCC(=O)CC.CN1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
DUSP3 P51452 1/20 0.39
HPGD P15428 2/20 0.37
MAPT P10636 1/20 0.37
CA9 Q16790 4/20 0.36
CA1 P00915 3/20 0.36
CA12 O43570 2/20 0.36
CA2 P00918 2/20 0.35
CA7 P43166 2/20 0.35
KMT2A Q03164 2/20 0.35
CA4 P22748 1/20 0.35
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NR1H3 Q13133 4/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
CASP1 P29466 1/20 0.31
BRCA1 P38398 1/20 0.31
CASP7 P55210 1/20 0.31
NR1H2 P55055 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1815113 0.82 UCHL1 (0.39) DUSP3CA9CA1CA12CA2
SCHEMBL1901728 0.68 CA9 (0.45) CA9CA1CA12CA2CA7
SCHEMBL3139205 0.68 CA9 (0.33) DUSP3CA9CA1CA12CA2
SCHEMBL11004497 0.68 ALDH1A1 (0.31) MAPTKMT2AALDH1A1MEN1USP2
SCHEMBL3678744 0.67 F2 (0.43) MAPTCA9CA1CA12CA2
SCHEMBL20756369 0.67 MEN1 (0.48) HPGDMAPTKMT2AKDM4EALDH1A1
SCHEMBL1813132 0.66 CA1 (0.50) DUSP3CA9CA1CA12CA2
Pentachlorobenzene SCHEMBL27726107 0.66 CYP3A4 (0.52) TDP1HPGDMAPTKMT2AMEN1
SCHEMBL12748840 0.66 KDM4E (0.32) HPGDCA9KDM4EALDH1A1
SCHEMBL4449615 0.65 CA1 (0.42) MAPTCA9CA1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6191307-B1 Process for making benzoic acids ALBEMARLE CORPORATION 2001-02-20 US disclosed