Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA7 | P43166 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139205 | 0.83 | CA9 (0.33) | UCHL1UCHL3ECE1MUS81ALDH1A1 | |
| SCHEMBL7932452 | 0.82 | TDP1 (0.40) | ALDH1A1CA9CA1CA2CA7 | |
| SCHEMBL12748840 | 0.79 | KDM4E (0.32) | ALDH1A1CA9PTGS2 | |
| SCHEMBL20756369 | 0.76 | MEN1 (0.48) | ALDH1A1TSHR | |
| SCHEMBL19370217 | 0.76 | CASP3 (0.33) | — | |
| SCHEMBL19426182 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1814110 | 0.75 | UCHL1 (0.43) | UCHL1UCHL3ECE1MUS81ALDH1A1 | |
| SCHEMBL1813132 | 0.74 | CA1 (0.50) | UCHL1UCHL3ECE1MUS81ALDH1A1 | |
| SCHEMBL11004497 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9485161 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819318-A | Tetrafluorobenzoic acid intermediate impurity and preparation method thereof | 浙江司太立制药股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-110407735-B | Synthesis process of 3,4,5, 6-tetrafluoro-N-methylphthalimide | 内蒙古源宏精细化工有限公司 | 2020-08-04 | — | — | CN | claimed |
| US-6187931-B1 | Process for making fluorophthalimides | ALBEMARLE CORPORATION | 2001-02-13 | — | — | US | claimed |
| EP-0495426-A2 | Preparation of 3,5-dichlorophthalic acid and 3,5-dichlorophthalic anhydride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-07-22 | — | — | EP | claimed |
| US-5086188-A | Preparation of 3,5-dichlorophthalic acid and 3,5-dichlorophthalic anhydride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-02-04 | — | — | US | claimed |
| US-4208489-A | AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-06-17 | — | — | US | claimed |
| JP-2145538-A | — | — | None | — | — | JP | disclosed |
| CN-115819318-A | Tetrafluorobenzoic acid intermediate impurity and preparation method thereof | 浙江司太立制药股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819318-A | Tetrafluorobenzoic acid intermediate impurity and preparation method thereof | 浙江司太立制药股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-3939962-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-01-19 | — | — | EP | disclosed |
| CN-110407735-B | Synthesis process of 3,4,5, 6-tetrafluoro-N-methylphthalimide | 内蒙古源宏精细化工有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-110407735-B | Synthesis process of 3,4,5, 6-tetrafluoro-N-methylphthalimide | 内蒙古源宏精细化工有限公司 | 2020-08-04 | — | — | CN | disclosed |
| US-10472315-B2 | Inhibitors of methionine aminopeptidases and methods of treating disorders | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-11-12 | — | — | US | disclosed |
| EP-0086353-A1 | Polycarbonate moulding compounds with flame resistance | BAYER AG (DE) | 1983-08-24 | — | — | EP | disclosed |
| US-4366276-A | Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies | BAYER AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | disclosed |
| EP-0042561-A1 | Fire-proofed moulding masses based on aromatic thermoplastic polyesters, process for its preparation and use in the production of shaped articles | BAYER AG (DE) | 1981-12-30 | — | — | EP | disclosed |
| EP-0034265-A2 | Synergetically active mixtures of materials and their use in rendering polycarbonate moulding masses antistatic | BAYER AG (DE) | 1981-08-26 | — | — | EP | disclosed |
| EP-0029930-A1 | Use of polyethylene terephthalate moulding masses containing an organic imide in the preparation of crystalline mouldings by injection moulding at low mould temperatures | BAYER AG (DE) | 1981-06-10 | — | — | EP | disclosed |
| US-4223100-A | Flame retardant aromatic polycarbonate with good mechanical properties and melt stability | MOBAY CHEMICAL CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4208489-A | AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472315-B2 | Inhibitors of methionine aminopeptidases and methods of treating disorders | METAP1, METAP2, ENPEP | UCHL1 438/4885UCHL3 322/4885ECE1 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.