Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117159 | 0.76 | HTR2A (0.38) | MAOAMAOBHTR2A | |
| SCHEMBL7120385 | 0.72 | HTR2A (0.35) | MAOAMAOBHTR2A | |
| SCHEMBL7123265 | 0.69 | ALDH1A1 (0.33) | MAOAMAOB | |
| SCHEMBL7122632 | 0.68 | MAOA (0.36) | MAOAMAOBHTR2A | |
| SCHEMBL5740020 | 0.62 | HTR2A (0.48) | MAOAHTR2A | |
| SCHEMBL15490742 | 0.60 | HTR2A (0.43) | HTR2A | |
| SCHEMBL30667090 | 0.59 | PTGS2 (0.39) | MAOAMAOBHTR2A | |
| SCHEMBL7652059 | 0.59 | MAOB (0.37) | MAOAMAOBHTR2A | |
| SCHEMBL11726679 | 0.58 | PTGS2 (0.41) | MAOAMAOBHTR2A | |
| SCHEMBL12409767 | 0.58 | HTR2A (0.40) | MAOAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300376-B1 | FOR THERAPY TO ACHIEVE SMOOTH MUSCLE RELAXING ACTIVITY AND/OR MAST CELL STABILIZING ACTIVITY AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IR) | 2001-10-09 | — | — | US | disclosed |