Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120385 | 0.83 | HTR2A (0.35) | MAOAMAOBNPSR1HTR2AALDH1A1 | |
| SCHEMBL7123265 | 0.80 | ALDH1A1 (0.33) | MAOAMAOBALDH1A1 | |
| SCHEMBL7117159 | 0.73 | HTR2A (0.38) | MAOAMAOBHTR2AALDH1A1 | |
| SCHEMBL15600622 | 0.69 | NPSR1 (0.54) | MAOAMAOBLMNAHTTNPSR1 | |
| SCHEMBL15600621 | 0.69 | NPSR1 (0.54) | MAOAMAOBLMNAHTTNPSR1 | |
| SCHEMBL7123284 | 0.69 | NPSR1 (0.54) | MAOAMAOBLMNAHTTNPSR1 | |
| SCHEMBL7127323 | 0.68 | SIGMAR1 (0.35) | MAOAMAOBSIGMAR1HTR2AHTR2C | |
| SCHEMBL7932507 | 0.68 | MAOA (0.33) | MAOAMAOBHTR2A | |
| SCHEMBL7932527 | 0.64 | L3MBTL1 (0.38) | MAOAMAOBLMNAHTTNPSR1 | |
| SCHEMBL7932529 | 0.64 | L3MBTL1 (0.38) | MAOAMAOBLMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865419-B1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LTD (IE) | 2003-08-06 | — | — | EP | claimed |
| US-6300376-B1 | FOR THERAPY TO ACHIEVE SMOOTH MUSCLE RELAXING ACTIVITY AND/OR MAST CELL STABILIZING ACTIVITY AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IR) | 2001-10-09 | — | — | US | claimed |
| EP-0865419-B1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LTD (IE) | 2003-08-06 | — | — | EP | disclosed |
| US-6300376-B1 | FOR THERAPY TO ACHIEVE SMOOTH MUSCLE RELAXING ACTIVITY AND/OR MAST CELL STABILIZING ACTIVITY AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IR) | 2001-10-09 | — | — | US | disclosed |
| WO-1997020802-A1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LIMITED (IE) | 1997-06-12 | — | — | WO | disclosed |