Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.50 |
| ▸ | HTR7 | P34969 | 11/20 | 0.50 |
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20953071 | 0.88 | DPP4 (0.47) | HTR1AHTR7DPP4 | |
| SCHEMBL6562015 | 0.87 | ACE (0.54) | — | |
| SCHEMBL4613053 | 0.87 | ACE (0.54) | — | |
| SCHEMBL24701563 | 0.87 | ACE (0.54) | — | |
| SCHEMBL4478131 | 0.87 | ACE (0.54) | — | |
| SCHEMBL6381431 | 0.84 | DPP4 (0.43) | HTR1AHTR7DPP4 | |
| SCHEMBL8006637 | 0.83 | ALDH1A1 (0.47) | HTR1AHTR7DPP4SPHK1 | |
| SCHEMBL13924627 | 0.83 | SPHK1 (0.52) | HTR1AHTR7DPP4SPHK1 | |
| SCHEMBL16116975 | 0.82 | SPHK1 (0.43) | SPHK1 | |
| SCHEMBL15624129 | 0.82 | SPHK1 (0.41) | HTR1AHTR7SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015545-A1 | PROCESS FOR THE PREPARATION OF A MACROCYCLE | F. HOFFMANN-LA ROCHE AG (CH) | 2010-02-11 | — | — | WO | disclosed |
| WO-2006043145-A1 | INHIBITORS OF HEPATITIS C VIRUS PROTEASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-04-27 | — | — | WO | disclosed |