SCHEMBL7932663

SCHEMBL7932663

C#Cc1cc(C)c(C#C)cc1C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PTPN1 P18031 1/20 0.30
PTPN6 P29350 1/20 0.30
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31307087 0.94 CYP3A4 (0.35) MAPTCYP3A4TSHR
SCHEMBL313219 0.94 CYP3A4 (0.35) MAPTCYP3A4TSHR
SCHEMBL28960921 0.90 MAPT (0.32) MAPTALDH1A1TP53CYP3A4TSHR
SCHEMBL2022697 0.77 PYCR1 (0.43) MAPTALDH1A1
SCHEMBL29044838 0.75 ALDH1A1 (0.31) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL31447558 0.75 ALDH1A1 (0.31) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL935347 0.75 TDP1 (0.42) ALDH1A1TP53CYP3A4TDP1
SCHEMBL30150790 0.75 TDP1 (0.42) ALDH1A1TP53CYP3A4TDP1
SCHEMBL3220960 0.75 TDP1 (0.42) ALDH1A1TP53CYP3A4TDP1
SCHEMBL12959692 0.74 L3MBTL1 (0.40) MAPTALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115715934-B Ethylene-chlorotrifluoroethylene copolymer hollow fiber membrane and casting solution thereof 阿克菲姆膜材(嘉兴)有限公司 2023-07-04 CN claimed
CN-115715934-A Ethylene-chlorotrifluoroethylene copolymer hollow fiber membrane and membrane casting solution thereof 阿克菲姆膜材(嘉兴)有限公司 2023-02-28 CN claimed
CN-115322644-A Modified alkynyl polymer coating constructed in situ at interface and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-11-11 CN claimed
CN-115715934-B Ethylene-chlorotrifluoroethylene copolymer hollow fiber membrane and casting solution thereof 阿克菲姆膜材(嘉兴)有限公司 2023-07-04 CN disclosed
CN-115715934-A Ethylene-chlorotrifluoroethylene copolymer hollow fiber membrane and membrane casting solution thereof 阿克菲姆膜材(嘉兴)有限公司 2023-02-28 CN disclosed
CN-115322644-A Modified alkynyl polymer coating constructed in situ at interface and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-11-11 CN disclosed
US-20130072523-A1 ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-03-21 US disclosed
EP-0834499-B1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK & CHEMICALS (JP) 2001-07-25 EP disclosed
EP-0834499-A1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-04-08 EP disclosed
US-5113002-A Polysilane copolymers and method for preparing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130072523-A1 ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS C1QBP, IRF3, IFNAR1 MAPT 2638/4885ALDH1A1 1562/4885TP53 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.