Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048193 | 0.85 | TSHR (0.45) | GPR84ALDH1A1TSHRTOP1 | |
| SCHEMBL7617453 | 0.85 | SLC22A6 (0.38) | GPR84ADRA1AHDAC2TDP1TSHR | |
| SCHEMBL967149 | 0.85 | ADRA1A (0.48) | GPR84ALDH1A1ADRA1AHDAC1HDAC2 | |
| SCHEMBL8065335 | 0.84 | TSHR (0.44) | GPR84ALDH1A1TSHRTOP1 | |
| SCHEMBL11294180 | 0.83 | ADRA1A (0.46) | GPR84ALDH1A1ADRA1AHDAC1HDAC2 | |
| SCHEMBL5529997 | 0.82 | GPR84 (0.38) | GPR84ALDH1A1ADRA1AHDAC1HDAC2 | |
| SCHEMBL6859069 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ADRA1AHDAC1HDAC2CHRM1 | |
| SCHEMBL1335604 | 0.80 | ADRA1A (0.48) | GPR84ALDH1A1ADRA1AHDAC1HDAC2 | |
| SCHEMBL19455882 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ADRA1AHDAC1HDAC2CHRM1 | |
| SCHEMBL5354813 | 0.79 | GPR84 (0.52) | GPR84ALDH1A1ADRA1AHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1675209-A | Dihydropyrazolopyridine compounds | MITSUBISHI PHARMA CORP (JP) | 2005-09-28 | — | — | CN | disclosed |
| US-6329027-B1 | Chlorobenzene derivatives, liquid-crystal composition, and liquid-crystal display elements | CHISSO CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0959060-A1 | CHLOROBENZENE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENTS | CHISSO CORPORATION (JP) | 1999-11-24 | — | — | EP | disclosed |