SCHEMBL7933738

SCHEMBL7933738

O=C1CCC(=O)N1C(Br)(Br)c1cccc(C(Br)(Br)N2C(=O)CCC2=O)c1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
RECQL P46063 1/20 0.32
NOTUM Q6P988 1/20 0.32
PGK1 P00558 2/20 0.31
PGK2 P07205 2/20 0.31
ALOX5 P09917 1/20 0.31
GAA P10253 1/20 0.31
PARL Q9H300 1/20 0.31
CYP11B1 P15538 2/20 0.30
CYP11B2 P19099 2/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5545766 0.64 CYP1A2 (0.41) KMT2APARLCYP11B1CYP11B2CYP19A1
SCHEMBL1538551 0.60 PGK1 (0.39) RECQLPGK1PGK2
SCHEMBL31279742 0.59 MEN1 (0.52) L3MBTL1MEN1KMT2AGAA
SCHEMBL7921220 0.58 ITGB1 (0.37) L3MBTL1MEN1KMT2AALOX5PARL
SCHEMBL1010019 0.57 CA12 (0.35)
Benzene SCHEMBL11532219 0.56 PARL (0.39) L3MBTL1MEN1KMT2ARECQLNOTUM
SCHEMBL2241265 0.56 ESR1 (0.46) PGK1PGK2GAA
SCHEMBL7086526 0.56 PARL (0.30) PARL
SCHEMBL6675001 0.56 PARL (0.30) PARL
SCHEMBL12386592 0.56 BRD4 (0.32) L3MBTL1RECQLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0800551-B1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL NV (NL) 2001-06-13 EP claimed
US-5844049-A Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds AKZO NOBEL NV (NL) 1998-12-01 US claimed
EP-0800551-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS Akzo Nobel N.V. (NL) 1997-10-15 EP claimed
WO-1996020246-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL N.V. (NL) 1996-07-04 WO claimed
EP-0800551-B1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL NV (NL) 2001-06-13 EP disclosed
US-5844049-A Sulfur-vulcanized rubber compositions comprising substituted succinimide compounds AKZO NOBEL NV (NL) 1998-12-01 US disclosed
EP-0800551-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS Akzo Nobel N.V. (NL) 1997-10-15 EP disclosed
WO-1996020246-A1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL N.V. (NL) 1996-07-04 WO disclosed