Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448588 | 0.82 | ALDH1A1 (0.49) | MAPTKMT2APOLBKDM4ETDP1 | |
| SCHEMBL6446115 | 0.82 | HSD17B10 (0.49) | MAPTKMT2AALDH1A1HPGDMAPK1 | |
| SCHEMBL2659793 | 0.82 | CYP1A2 (0.51) | MAPTKMT2APOLBALDH1A1HSP90AA1 | |
| SCHEMBL18146104 | 0.82 | ALDH1A1 (0.54) | MAPTKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL31261399 | 0.82 | ALDH1A1 (0.54) | MAPTKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL12306339 | 0.82 | MAPT (0.42) | MAPTKMT2APOLBALDH1A1HSP90AA1 | |
| SCHEMBL29718848 | 0.81 | CA2 (0.44) | MAPTKMT2APOLBALDH1A1 | |
| SCHEMBL31285140 | 0.79 | TSHR (0.49) | MAPTKMT2APOLBKDM4ETDP1 | |
| SCHEMBL3156146 | 0.79 | LMNA (0.57) | MAPTKMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6179703 | 0.79 | LMNA (0.51) | MAPTKMT2APOLBKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070008-A1 | SUBSTITUTED BICYCLIC IMIDAZOLE DERIVATIVES AS GAMMA SECRETASE MODULATORS | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2010-06-24 | — | — | WO | disclosed |