Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931128 | 0.89 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1TDP1CSNK2A1 | |
| SCHEMBL7934212 | 0.89 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1TDP1CSNK2A1 | |
| SCHEMBL7934233 | 0.84 | KDM4E (0.40) | L3MBTL1KDM4EALDH1A1TDP1MAPK1 | |
| SCHEMBL7928487 | 0.83 | RARB (0.41) | L3MBTL1KDM4EALDH1A1TDP1MAPK1 | |
| SCHEMBL7931127 | 0.80 | L3MBTL1 (0.48) | L3MBTL1KDM4EALDH1A1CSNK2A1SMN1; SMN2 | |
| SCHEMBL6344107 | 0.79 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1TDP1CSNK2A1 | |
| SCHEMBL5657236 | 0.79 | LMNA (0.45) | L3MBTL1KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7221364 | 0.77 | ALDH1A1 (0.48) | L3MBTL1KDM4EALDH1A1TDP1MAPK1 | |
| SCHEMBL7216146 | 0.76 | HTR1A (0.40) | L3MBTL1KDM4EALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL3787950 | 0.75 | CSNK2A1 (0.62) | L3MBTL1KDM4EALDH1A1TDP1CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140896-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| WO-2000037455-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-06-29 | — | — | WO | disclosed |