SCHEMBL7934406

SCHEMBL7934406

O=C(O)c1ccc(OCc2ccc(O)cc2)c(C(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.69
MRGPRX4 Q96LA9 2/20 0.55
HPGD P15428 2/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
RXRA P19793 7/20 0.50
RXRB P28702 6/20 0.50
RXRG P48443 4/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1649243 0.89 FOLH1 (0.68) FOLH1MRGPRX4HPGDNPC1RAB9A
SCHEMBL7943998 0.88 FOLH1 (0.57) FOLH1MRGPRX4HPGDNPC1RAB9A
SCHEMBL344398 0.81 FOLH1 (0.70) FOLH1SMN1; SMN2KDM4EALDH1A1POLB
SCHEMBL8847033 0.80 FOLH1 (0.67) FOLH1MRGPRX4HPGDNPC1RAB9A
SCHEMBL131229 0.79 FOLH1 (0.63) FOLH1MRGPRX4HPGDNPC1RAB9A
SCHEMBL27610143 0.79 GAA (0.64) FOLH1HPGDNPC1RAB9ARXRA
SCHEMBL1316640 0.78 ALDH1A1 (0.56) FOLH1MRGPRX4HPGDRXRARXRB
SCHEMBL4295650 0.78 FOLH1 (0.62) FOLH1HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL5340855 0.77 TSHR (0.68) FOLH1MRGPRX4HPGDNPC1RAB9A
SCHEMBL383169 0.77 FOLH1 (0.53) FOLH1MRGPRX4RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6255444-B1 COMPOSITION CONTAINING DENDRIMER AND POLYMERIZATION INITIATOR AS ESSENTIAL COMPONENTS; LOW VISCOSITY, HIGHLY CURABLE, FORMS COATING FILM WITH EXCELLENT HEAT AND MOISTURE RESISTANCE NIPPON STEEL CHEMICAL CO., LTD. (JP) 2001-07-03 US disclosed
EP-1006101-A1 AROMATIC ESTER (METH)ACRYLATE DENDRIMER AND CURABLE RESIN COMPOSITION Nippon Steel Chemical Co., Ltd. (JP) 2000-06-07 EP disclosed