Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3661444 | 0.81 | GPR3 (0.33) | — | |
| Methane SCHEMBL5347437 | 0.80 | GPR3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7641203 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL5390988 | 0.73 | — | — | |
| Fluoride Ion SCHEMBL5389097 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL9412848 | 0.69 | NR3C1 (0.39) | — | |
| Methane SCHEMBL7942791 | 0.68 | MEN1 (0.30) | — | |
| SCHEMBL5846829 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL5846007 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL5845936 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211108-B1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-04-03 | — | — | US | disclosed |