Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308612 | 0.81 | TSHR (0.38) | HSD17B10LMNATSHRRGS12GAA | |
| SCHEMBL8835717 | 0.79 | HSD17B10 (0.46) | HSD17B10LMNATSHRRGS12GAA | |
| SCHEMBL3501182 | 0.75 | TSHR (0.44) | HSD17B10LMNATSHRRGS12GAA | |
| SCHEMBL8154208 | 0.75 | ALDH1A1 (0.40) | HSD17B10LMNATSHRRGS12GAA | |
| SCHEMBL2064738 | 0.73 | TSHR (0.42) | HSD17B10LMNATSHRRGS12GAA | |
| SCHEMBL2184430 | 0.71 | TSHR (0.50) | HSD17B10LMNATSHRRGS12GAA | |
| SCHEMBL10677331 | 0.71 | TSHR (0.50) | HSD17B10LMNATSHRRGS12GAA | |
| SCHEMBL16597493 | 0.70 | TSHR (0.44) | HSD17B10LMNATSHRRGS12GAA | |
| Silver SCHEMBL6905008 | 0.70 | TSHR (0.44) | HSD17B10LMNATSHRRGS12GAA | |
| SCHEMBL5916254 | 0.70 | TSHR (0.39) | HSD17B10TSHRRGS12GAARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054278-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |