Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308612 | 0.76 | TSHR (0.38) | ALDH1A1TSHRHSD17B10RGS12LMNA | |
| SCHEMBL7934703 | 0.75 | HSD17B10 (0.41) | TSHRHSD17B10RGS12LMNAGAA | |
| SCHEMBL8835717 | 0.75 | HSD17B10 (0.46) | ALDH1A1TSHRHSD17B10RGS12LMNA | |
| SCHEMBL11004287 | 0.75 | TSHR (0.37) | ALDH1A1TSHRRGS12 | |
| SCHEMBL3501182 | 0.71 | TSHR (0.44) | TSHRHSD17B10RGS12LMNAGAA | |
| SCHEMBL8663025 | 0.70 | HSD17B10 (0.42) | ALDH1A1TSHRHSD17B10RGS12LMNA | |
| SCHEMBL2064738 | 0.69 | TSHR (0.42) | ALDH1A1TSHRHSD17B10RGS12LMNA | |
| SCHEMBL345502 | 0.68 | TSHR (0.42) | ALDH1A1TSHRHSD17B10RGS12GAA | |
| SCHEMBL2143425 | 0.68 | ALDH1A1 (0.50) | ALDH1A1TSHRRGS12GAAHPGD | |
| SCHEMBL2184430 | 0.67 | TSHR (0.50) | TSHRHSD17B10RGS12LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121302-A | BROAD SPECTRUM PRESERVATIVE COMPRISING ISOTHIAZOLONES WITH ALKANOL-SUBSTITUTED DIMETHYLHYDANTOIN AS FORMALDEHYDE DONOR, AND AN ALKYL HYDANTOIN AS A STABILIZER FOR ISOTHIAZOLONE; LOW FREE FORMALDEHYDE, STABLE IN LARGE PH RANGE | LONZA, INC. (US) | 2000-09-19 | — | — | US | claimed |