SCHEMBL7934727

SCHEMBL7934727

CO[Si](CCCN(CCCCCCN(CCC[Si](OC)(OC)OC)C(N)=O)C(N)=O)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22190095 0.96 LMNA (0.33) LMNAACHE
SCHEMBL768198 0.96 LMNA (0.32) LMNA
SCHEMBL16862704 0.94 LMNA (0.31) LMNA
SCHEMBL17133249 0.89 ACHE (0.30) ACHE
SCHEMBL1069805 0.89 EPHX1 (0.33)
SCHEMBL31142799 0.86 LMNA (0.30) LMNA
SCHEMBL16862753 0.86 LMNA (0.30) LMNA
SCHEMBL17133257 0.85 MTNR1A (0.32)
SCHEMBL13729672 0.84
SCHEMBL16986433 0.82 CA2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268456-B1 FILMS WITH REACTIVE SILYL GROUPS E. I. DU PONT DE NEMOURS AND COMPANY 2001-07-31 US disclosed
EP-0830434-B1 COATING COMPOSITION CONTAINING SILANE FUNCTIONALITY DU PONT (US) 1999-12-01 EP disclosed
EP-0830434-A1 COATING COMPOSITION CONTAINING SILANE FUNCTIONALITY E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-25 EP disclosed
WO-1996039468-A1 COATING COMPOSITION CONTAINING SILANE FUNCTIONALITY E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-12-12 WO disclosed