Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936471 | 0.81 | HRH3 (0.47) | HRH3ALDH1A1KDM4ECCR3ACHE | |
| SCHEMBL5024049 | 0.66 | ALDH1A1 (0.45) | HRH3ALDH1A1KDM4EACHEKMT2A | |
| SCHEMBL15858942 | 0.66 | ACHE (0.60) | HRH3ALDH1A1KDM4EACHEKMT2A | |
| SCHEMBL8672865 | 0.64 | ABCB1 (0.47) | ALDH1A1CCR3TACR1SIGMAR1ABCB1 | |
| SCHEMBL2336883 | 0.64 | KDM4E (0.65) | HRH3ALDH1A1KDM4EACHEKMT2A | |
| SCHEMBL8672692 | 0.63 | SLC18A3 (0.43) | ALDH1A1KDM4EKMT2ASIGMAR1ABCB1 | |
| SCHEMBL24163317 | 0.63 | RECQL (0.69) | HRH3ALDH1A1KDM4ECCR3ACHE | |
| Hydrochloric Acid SCHEMBL2331568 | 0.63 | KDM4E (0.63) | HRH3ALDH1A1KDM4EKMT2ASIGMAR1 | |
| SCHEMBL12230208 | 0.62 | MAPK1 (0.52) | HRH3ALDH1A1KDM4EACHEKMT2A | |
| SCHEMBL13943667 | 0.62 | SIGMAR1 (0.64) | HRH3ALDH1A1KDM4EACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6235732-B1 | RESPIRATORY SYSTEM DISORDERS; ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-22 | — | — | US | disclosed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5985881-A | TREATMENT AND PREVENTION OF RESPIRATORY DISORDERS, INFLAMMATORY EYE DISEASES, INFLAMMATORY SKIN DISEASES, INTESTINAL DISORDERS, OTHER INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM KG (DE) | 1999-11-16 | — | — | US | disclosed |
| WO-1996008480-A1 | NEUROKININ ANTAGONISTS | BOEHRINGER INGELHEIM KG (DE) | 1996-03-21 | — | — | WO | disclosed |