SCHEMBL7935320

SCHEMBL7935320

O=C(c1ccccc1)c1ccc(S(=O)(=O)c2ccc(F)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
CA14 Q9ULX7 1/20 0.54
HPGD P15428 3/20 0.53
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALPG P10696 1/20 0.53
ALDH1A1 P00352 2/20 0.52
HSD11B1 P28845 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
PRMT1 Q99873 1/20 0.50
ITGB1 P05556 1/20 0.50
ITGA2 P17301 1/20 0.50
SRD5A2 P31213 1/20 0.50
PTGS2 P35354 1/20 0.49
USP2 O75604 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7937303 0.96 HSD11B1 (0.56) CA12CA1CA2CA9CA14
SCHEMBL9617501 0.92 LTA4H (0.55) CA12CA1CA2CA9CA14
SCHEMBL5524425 0.92 LTA4H (0.55) CA12CA1CA2CA9CA14
SCHEMBL9163179 0.90 ALDH1A1 (0.64) CA12CA1CA2CA9CA14
Benzene SCHEMBL27709388 0.86 ALDH1A1 (0.70) HPGDLMNASMN1; SMN2ALPGALDH1A1
SCHEMBL17068941 0.86 ALDH1A1 (0.70) HPGDLMNASMN1; SMN2ALPGALDH1A1
SCHEMBL251921 0.86 ALDH1A1 (0.70) HPGDLMNASMN1; SMN2ALPGALDH1A1
SCHEMBL27483853 0.86 ALDH1A1 (0.70) HPGDLMNASMN1; SMN2ALPGALDH1A1
SCHEMBL7940606 0.86 ALDH1A1 (0.70) HPGDLMNASMN1; SMN2ALPGALDH1A1
SCHEMBL13297333 0.85 CA1 (0.58) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed