Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524425 | 1.00 | LTA4H (0.55) | LTA4HCA1CA2NPC1RAB9A | |
| SCHEMBL7937303 | 0.92 | HSD11B1 (0.56) | LTA4HCA1CA2ALDH1A1HPGD | |
| SCHEMBL7935320 | 0.92 | CA12 (0.54) | CA1CA2ALDH1A1HPGDNPSR1 | |
| SCHEMBL10426597 | 0.91 | ALDH1A1 (0.57) | LTA4HALDH1A1TP53MAPTMAPK1 | |
| SCHEMBL8767888 | 0.89 | SOS1 (0.56) | LTA4HMAPTMAPK1SMN1; SMN2MMP1 | |
| SCHEMBL13978716 | 0.89 | SOS1 (0.56) | LTA4HMAPTMAPK1SMN1; SMN2MMP1 | |
| SCHEMBL29983601 | 0.86 | LTA4H (0.70) | LTA4HCA1CA2NPC1RAB9A | |
| SCHEMBL30632245 | 0.86 | LTA4H (0.70) | LTA4HCA1CA2NPC1RAB9A | |
| SCHEMBL31108971 | 0.85 | BCL2L1 (0.63) | CA1CA2ALDH1A1KDM4ETP53 | |
| SCHEMBL13297333 | 0.85 | CA1 (0.58) | LTA4HCA1CA2NPC1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4243859-A | — | — | None | — | — | JP | disclosed |
| JP-H04243859-A | AROMATIC COMPOUND AND PRODUCTION THEREOF | IDEMITSU KOSAN CO LTD | 1992-08-31 | — | — | JP | disclosed |
| US-5115078-A | Self polymerizable phenylquinoxalines, their preparation and use in polyphenylquinoxaline homopolymers and copolymers | THE UNIVERSITY OF AKRON (US) | 1992-05-19 | — | — | US | disclosed |
| US-5030704-A | Self polymerizable phenylquinoxalines, their preparation and use in polyphenylquinoxaline homopolymers and copolymers | THE UNIVERSITY OF AKRON (US) | 1991-07-09 | — | — | US | disclosed |
| WO-1990015836-A1 | SELF-POLYMERIZABLE PHENYLQUINOXALINES | THE UNIVERSITY OF AKRON (US) | 1990-12-27 | — | — | WO | disclosed |
| US-4924014-A | Process for the preparation of halogen-containing aromatic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-08 | — | — | US | disclosed |