SCHEMBL7935589

SCHEMBL7935589

CS(=O)(=O)c1ccc(Cc2ccc(F)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 15/20 0.56
PTGS1 P23219 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13231429 0.89 ENPP2 (0.54) PTGS2
SCHEMBL444872 0.87 PTGS2 (0.69) PTGS2PTGS1
Water SCHEMBL27918427 0.84 PTGS2 (0.67) PTGS2PTGS1
SCHEMBL27431456 0.83 PTPN5 (0.54) PTGS2PTGS1
SCHEMBL16770523 0.81 CA12 (0.58) PTGS2PTGS1
SCHEMBL7395459 0.80 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL7938593 0.80 PTGS2 (0.62) PTGS2PTGS1
SCHEMBL6470141 0.80 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL7938035 0.79 ENPP2 (0.75) PTGS2PTGS1
SCHEMBL778955 0.79 EGFR (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed