Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932076 | 0.82 | PDE4A (0.33) | PDE4ACYP1A2CYP2C19CHRNA7LMNA | |
| SCHEMBL7925284 | 0.76 | KMT2A (0.37) | CYP1A2CYP2C19 | |
| SCHEMBL979110 | 0.75 | PDE4A (0.43) | PDE4ACYP1A2CYP2C19LMNA | |
| SCHEMBL7935974 | 0.73 | — | — | |
| SCHEMBL9196363 | 0.69 | ALDH1A1 (0.33) | CYP1A2CHRNA7 | |
| SCHEMBL9189093 | 0.68 | PDE4A (0.48) | PDE4ACYP1A2CYP2C19CHRNA7LMNA | |
| SCHEMBL7806809 | 0.67 | CFTR (0.40) | PDE4ACYP1A2CYP2C19CHRNA7LMNA | |
| SCHEMBL9183979 | 0.67 | MEN1 (0.37) | PDE4ACYP1A2CYP2C19CHRNA7LMNA | |
| SCHEMBL7934015 | 0.66 | PGK1 (0.35) | PDE4ACYP1A2CYP2C19CHRNA7LMNA | |
| SCHEMBL7932080 | 0.64 | CHRNA7 (0.38) | PDE4ACYP1A2CYP2C19CHRNA7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |