Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.53 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12225965 | 0.80 | KMT2A (0.44) | TSHRSMN1; SMN2NPSR1HTTALDH1A1 | |
| SCHEMBL2538104 | 0.74 | MEN1 (0.58) | LMNATSHRSMN1; SMN2USP2NPSR1 | |
| SCHEMBL7924131 | 0.74 | ALDH1A1 (0.62) | LMNATSHRSMN1; SMN2USP2NPSR1 | |
| SCHEMBL2533708 | 0.72 | MAPT (0.64) | LMNATSHRSMN1; SMN2USP2NPSR1 | |
| SCHEMBL7935215 | 0.71 | ALDH1A1 (0.61) | LMNATSHRSMN1; SMN2USP2NPSR1 | |
| SCHEMBL1611721 | 0.71 | LMNA (0.76) | LMNATSHRSMN1; SMN2USP2NPSR1 | |
| SCHEMBL19248206 | 0.70 | LMNA (0.71) | LMNATSHRSMN1; SMN2USP2NPSR1 | |
| SCHEMBL7936741 | 0.70 | ALDH1A1 (0.54) | LMNATSHRSMN1; SMN2USP2NPSR1 | |
| SCHEMBL2534486 | 0.70 | ALDH1A1 (0.64) | LMNATSHRSMN1; SMN2USP2NPSR1 | |
| SCHEMBL2530971 | 0.69 | KMT2A (0.58) | LMNATSHRSMN1; SMN2USP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034003-A2 | BENZYLTHIOTETRAZOLE INHIBITORS OF STORE OPERATED CALCIUM RELEASE | CALCIMEDICA, INC. (US) | 2010-03-25 | — | — | WO | disclosed |